What patients are candidates for this procedure?ĭr. This therapy has been associated with improvement in exercise capacity (measured by 6-minute walk test), QOL (measured by the Minnesota Living with Heart Failure Questionnaire), and NT-proBNP in patients with HF. The system works through continuous electrical stimulation of the carotid baroreceptors, modulating the baroreflex, which decreases sympathetic activity while also increasing parasympathetic activity to the cardiovascular system. It is an early intervention that can be offered to the HF patient before they are too sick, when more invasive interventions such as a left ventricular assist device (LVAD) or orthotopic heart transplant (OHT) will be considered.įigure 1. Perez-Izquierdo: Barostim is a novel technology that is geared toward “resynchronizing” the autonomic nervous system by stimulating the baroreflex to decrease sympathetic tone and increase parasympathetic tone. This stimulation increases signaling to the brain, which downregulates sympathetic tone and upregulates parasympathetic tone to improve HF symptoms ( Figure 1).ĭr. The device electrode is surgically implanted on the surface of the carotid sinus (usually the right carotid), which delivers energy from a pulse generator placed in a subcutaneous chest pocket to electrically stimulate the carotid baroreceptors. Weaver: BAT, delivered via the Barostim™ system (CVRx, Inc.), is a device-based therapy designed to improve the symptoms of HF. What is Baroreflex Activation Therapy (BAT)?ĭr. This imbalance also has deleterious effects on renal and overall cardiovascular homeostasis. With altered signaling from the carotid sinus baroreceptors to the brain, an imbalance in the autonomic nervous system can result with adverse consequences on cardiac function. Training video on implantation of Barostim.
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